Stop Wasting Money on DHT-Blocking Shampoos–Here’s Why

I have been seeing SO many ads on social media and cable and television about shampoos that prevent hair loss that I adamantly felt an informed article about this topic was necessary. Many of these ads refer to their ability to lower dihydrotestosterone (DHT), a metabolite of the male hormone testosterone. About 10 percent of the testosterone in healthy men is converted to DHT. Women have 1/10th to 1/20th of the amount of testosterone compared to men, with even significantly smaller amounts being converted to DHT. Therefore, DHT is an unlikely culprit for hair loss in women.

Dihydrotestosterone (DHT) is a potent androgen derived from testosterone through the action of the enzyme 5-alpha reductase. While testosterone and DHT plays a crucial role in male development, DHT by miniaturizing hair follicles over time. Factors that can elevate DHT levels include high testosterone levels, aging, genetic predisposition, excessive alcohol consumption, chronic stress, and dietary habits rich in processed foods and unhealthy fats. Additionally, excessive weight gain and insulin resistance can further contribute to elevated DHT production. (Wow, once again eating a healthy diet and maintaining a healthy weight is important)

Many shampoos and wash-off products claim to block DHT and stimulate hair growth, but the reality is that they are unlikely to be effective. Since these products are rinsed off within minutes, they don’t remain on the scalp long enough to significantly inhibit DHT production or counteract its effects. For those concerned about hair loss, it’s best to invest in clinically supported oral and topical treatments rather than temporary solutions that offer little more than marketing hype.

Effective DHT Inhibitors

1.   Finasteride (Oral)– One of the most well-researched DHT inhibitors, finasteride works by blocking the 5-alpha reductase enzyme, reducing DHT levels by up to 70%. This prescription medication has been shown to slow hair loss and, in some cases, promote regrowth. However, potential side effects such as reduced libido and hormonal imbalances should be considered before use.

2.   Dutasteride (Oral)– Even more potent than finasteride, dutasteride inhibits both Type I and Type II 5-alpha reductase enzymes, leading to an even greater reduction in DHT levels. While not FDA-approved for hair loss, some studies suggest it may be more effective than finasteride for those who do not respond well to the latter. (Dutasteride is currenly used to treat enlarged prostates)

3.   Saw Palmetto (Oral & Topical)– A natural DHT blocker, saw palmetto is derived from the berries of the Serenoa repens plant. It works by inhibiting 5-alpha reductase, similar to finasteride but with a milder effect. It is available in oral supplement form and is also found in some topical treatments, though its effectiveness is not as well-documented as prescription options.

4.   Pumpkin Seed Oil (Oral & Topical)– Rich in phytosterols that help inhibit DHT, pumpkin seed oil has shown promising results in some studies for improving hair density and slowing hair loss. It can be taken as a supplement or applied directly to the scalp.

5.   EGCG (Epigallocatechin Gallate) from Green Tea (Oral & Topical) – A powerful antioxidant found in green tea, EGCG has been shown to inhibit 5-alpha reductase, potentially reducing DHT levels. It can be consumed as green tea or applied topically in serums containing green tea extracts.

6.   Ketoconazole (Topical)– Commonly found in anti-dandruff shampoos, ketoconazole has mild anti-DHT properties. While it doesn’t significantly lower systemic DHT levels, it may help reduce inflammation and improve scalp health, making it a useful addition to a broader hair care regimen.

For those serious about addressing hair loss, targeting DHT with proven oral or topical treatments is the best approach. While natural alternatives like saw palmetto and green tea may offer mild benefits, prescription options like finasteride and dutasteride provide the most reliable results. Avoid falling for the hype of DHT-blocking shampoos and invest in scientifically supported solutions that can genuinely make a difference. In other words, save your money!